Hyperbilirubinemia is a predictor of appendiceal perforation in children: A meta-analysis

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Küçük Resim

Tarih

2023

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Academic Journal of Health Sciences

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Objective: In this meta-analysis, our goal was to examine the diagnostic utility of bilirubin in identifying complicated from uncomplicated pediatric appendicitis. Materials and methods: Using the databases Embase, PubMed, Scopus, and Cochrane, we carried out a thorough literature search up to 2022. Studies comparing complicated appendicitis (CA) and simple appendicitis (SA) in terms of hyperbilirubinemia in the pediatric population were included. Results: A total of 5 studies with 2740 acute appendicitis patients (1097 complicated appendicitis and 1643 simple appendicitis) were included in this meta-analysis. Five studies have discussed the diagnostic value of total bilirubin (TB). When compared to simple appendicitis, complicated appendicitis had a significantly higher TB count (I2 =94%), (WMD=0.18, 95% CI -0.00 to 0.37; P=0.05), DB count (I2 =0%), (WMD=0.11, 95% CI 0.04 to 0.18; P=0.002), and IB count (I2 = not applicable), (WMD=0.04, 95% CI 0.01 to 0.07; P=0.02). Conclusions: In conclusion, in this meta-analysis, total bilirubin, direct bilirubin, and indirect bilirubin values were higher in complicated appendicitis compared to simple appendicitis. Both total bilirubin and direct bilirubin can be used as diagnostic parameters in childhood appendicitis to differentiate complicated appendicitis from simple appendicitis.

Açıklama

Anahtar Kelimeler

Appendicitis, children, direct hyperbilirubinemia, hyperbilirubinemia.

Kaynak

Academic Journal of Health Sciences

WoS Q Değeri

Scopus Q Değeri

Cilt

4

Sayı

38

Künye

Azizoğlu M, Okur MH, Aydoğdu B, Orbay TM, Bakir AC, Klyuev SA, Bilici S, Bayram S, Salik F, Risteski T. Hyperbilirubinemia is a predictor of ap pendiceal perforation in children: A meta-analy sis. Acad J Health Sci 2023; 38: 64-68.