Aging and cardiac implantable electronic device complications: is the procedure safe in older patients?
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Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
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ELSEVIER
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background In this study, we investigated whether there is a higher incidence of cardiac implantable electronic devices
(CIED) procedures related complications in older (≥75 years) than in younger (<75 years) patients.
Methods This retrospective cohort study enrolled patients who had undergone CIED procedures (de novo implantation,
system upgrade, generator substitution, pocket revision or lead replacement) at two heart centers in Turkey between January
2011 and May 2023. The primary composite endpoint included clinically signifcant hematoma (CSH), pericardial efusion
or tamponade, pneumothorax, and infection related to the device system. Secondary outcomes included each component of
the composite end point.
Results The overall sample included 1923 patients (1419<75 years and 504 aged≥75 years). There was no diference
between the groups in terms of cumulative events defned as primary outcome (3.5% vs. 4.4%, p=0.393). Infection related
to device system was signifcantly higher in the≥75 age group (1.8% vs. 3.4%, p=0.034). There was no signifcant diference between the groups in terms of clinically signifcant hematoma and pneumothorax (0.7% vs. 0.4%, p=0.451, 1.4% vs.
1.0%, p=0.477, respectively). In multivariate model analysis, no association was found between age≥75 years and infection
related to the device system.
Conclusion Infection rates were relatively higher in the patient group aged≥75 years. This patient group should be evaluated
more carefully in terms of infection development before and after the procedure.
Açıklama
Anahtar Kelimeler
Pacemaker · Cardiovascular implantable electronic devices · Complication · Elderly
Kaynak
Aging Clinical and Experimental Research
WoS Q Değeri
Q2
