Biochemical components, enzyme inhibitory, antioxidant and antimicrobial activities in endemic plant Scilla mesopotamica speta

dc.authorid0000-0003-2192-9049en_US
dc.authorid0000-0003-3758-0654en_US
dc.authorid0000-0002-2317-0489en_US
dc.authorid0000-0003-2993-2605en_US
dc.authorid0000-0001-8133-6670en_US
dc.authorid0000-0003-4992-0281en_US
dc.contributor.authorAktepe, Necmettin
dc.contributor.authorKeskin, Cumali
dc.contributor.authorBaran, Ayşe
dc.contributor.authorAtalar, Mehmet Nuri
dc.contributor.authorBaran, Mehmet Fırat
dc.contributor.authorAkmeşe, Şükrü
dc.date.accessioned2021-10-21T08:00:38Z
dc.date.available2021-10-21T08:00:38Z
dc.date.issued2021en_US
dc.departmentMAÜ, Fakülteler, Sağlık Bilimleri Fakültesi, Hemşirelik Bölümüen_US
dc.description.abstractIn this study, in vitro antioxidant, antimicrobial, anticholinesterase and phenolic profile of different solvent extracts of Scilla mesopotamica speta were determined in detail. In vitro antioxidant activities and total phenolic and flavonoid contents of plant extracts obtained with different solvents were tested in terms of 2.2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activities. The highest total phenolic and total flavonoid contents were determined in the ethyl acetate extract (62.24 mu g GAE/mg) and chloroform extract (87.72 mu g QE/mg) respectively. The highest DPPH radical scavenging activity was detected in ethyl acetate extracts. Antimicrobial and antifungal activities were investigated by MIC method. The inhibitory activities of the extracts on the acetyl cholinesterase enzyme were investigated. Liquid chromatography (LC) tandem mass spectrometry LC-MS/MS was used to determine the phenolic component content of extracts. Thirty-one different components were identified in the analyses and their amounts were measured. Practical applications Scilla mesopotamica speta is an endemic and medicinal plant. It was determined that the extracts of this plant had a very rich content in terms of phenolic compounds, especially caffeic and ferulic acids. However, this plant was remarkable for its antioxidant, anticholinesterase, and antimicrobial activities. Considering the strong antioxidant, antimicrobial, and enzyme inhibition activities of the Scilla mesopotamica speta it can be suggested as a source of anticancer, antimicrobial, and antiviral drugs.en_US
dc.identifier.citationAktepe, N., Keskin, C., Baran, A., Atalar, M. N., Baran, M. F., & Akmeşe, Ş. (2021). Biochemical components, enzyme inhibitory, antioxidant and antimicrobial activities in endemic plant Scilla mesopotamica speta. In Journal of Food Processing and Preservation. Wiley. https://doi.org/10.1111/jfpp.15980en_US
dc.identifier.doi10.1111/jfpp.15980en_US
dc.identifier.scopus2-s2.0-85116090413en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.1111/jfpp.15980
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000702988600001?AlertId=d383397b-4355-449e-9419-70f9e0e77c15&SID=F2yD84a3mpZOfw1zNMF
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85116090413&origin=resultslist&sort=plf-f&src=s&sid=0e055d254f09404bbc63bb45c077aaa7&sot=b&sdt=b&sl=23&s=DOI%2810.1111%2fjfpp.15980%29&relpos=0&citeCnt=0&searchTerm=
dc.identifier.urihttps://hdl.handle.net/20.500.12514/2899
dc.identifier.wosWOS:000702988600001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Food Processing and Preservationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectANTIBACTERIAL ACTIVITY, PHENOLIC-COMPOUNDS, ACID, ACETYLCHOLINESTERASE, LILIUMen_US
dc.titleBiochemical components, enzyme inhibitory, antioxidant and antimicrobial activities in endemic plant Scilla mesopotamica spetaen_US
dc.typeArticleen_US

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