Ercan, LeylaGünbegi Çalışkan, EmineKılıç, Murat2024-03-222024-03-222024Ercan, L., Gunbegi Caliskan, C., & Kilic, M. (2024). Comparison of chemical and antimicrobial properties of different nanoparticles synthesized from verbascum x calcicolum hub.-mor. hybrid. Journal of the Indian Chemical Society, 101(3), 101133. https://doi.org/10.1016/j.jics.2024.101133https://doi.org/10.1016/j.jics.2024.101133https://hdl.handle.net/20.500.12514/5844Recent advances in nanoparticle synthesis have led to an increase in the use of environmentally acceptable plant-derived nanoparticles, given their wide range of applications. Due to their stability and several advantageous characteristics, selenium nanoparticles also stand out in these investigations in addition to metallic nanoparticles like silver, gold, iron, and zinc. These nanoparticles' favorable qualities for human health, such as antioxidant and antibacterial activities, are being studied in addition to their chemical characteristics. This investigation aimed to produce zinc oxide nanoparticles (VcZnO) and selenium nanoparticles (VcSe) from hybrid Verbascum x calcicolum Hub.-Mor. And to examine their antioxidant and antimicrobial properties. Utilizing the disk diffusion method and well methods, its antibacterial capabilities were studied. In vitro antioxidant capabilities were also assessed utilizing the DPPH, FRAP, and CUPRAC techniques. As a result, it emerged that zinc oxide nanoparticles synthesized from hybrid Verbascum x calcicolum were effective on gram-positive bacteria and gram-negative bacteria such as Staphylococcus aureus (MIC = 160 mg/ml for VcZnO), Pseudomonas aeruginosa (MIC = 80 mg/ml for VcZnO), Klebsiella pneumoniae (MIC = 40 mg/ml for VcZnO and, MIC = 120 mg/ml for VcSe), Escherichia coli (MIC = 20 mg/ml for VcZnO). While selenium nanoparticles are more favorable in terms of antioxidant capabilities, zinc nanoparticles demonstrate stronger antibacterial properties than selenium nanoparticles. Thus, it has been discovered that the use of different nanoparticles of various plants can be more efficient in different applications. It has also been found that Verbascum x calcicolum is a material that can be used successfully in nanoparticle synthesis.en10.1016/j.jics.2024.101133info:eu-repo/semantics/closedAccessGreen synthesisHybrid Verbascum x calcicolumSelenium nanoparticlesZinc oxide nanoparticlesArticle1013Q42-s2.0-85186765110&