The protective role of selenium in an experimental high fructose corn syrup exposure.
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Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Modestum
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: Nowadays, fructose is recognized as a significant health threat. Prepared foods
containing fructose are consumed more because they do not create a feeling of satiety.
Selenium is an essential trace element with antioxidant and cell protective properties. In this
study, the effect of high fructose corn syrup, which is used as a sweetener in many foods and
beverages and consumed during pregnancy, and the possible protective role of selenium in
this effect were investigated and examined.
Methods: Fertilized specific pathogen-free eggs were used in our study. These eggs were
divided equally into four groups. Each group was allocated 10 eggs containing viable embryos.
These groups are pre-process control, post-process control, high fructose corn syrup (HFCS55), and high fructose corn syrup and selenium (HFCS-55+Se 10-6
) groups. Pellets containing
and containing no active substance (HFCS-55, HFCS-55+Se 10-6
) were carefully placed on the
chorioallantoic membrane (CAM) of each egg in these groups. Oxidative stress status in all
groups was determined by total oxidative stress (TOS) and total antioxidant capacity (TAC)
methods.
Results: In our study, a significant increase in TOS levels and a significant decrease in TAC
levels were observed in egg groups given HFCS compared to other groups (p<0.05). The OSI
value was shown to be lower in the group given HFCS+Se.
Conclusion: As a result, HFCS was shown to increase oxidative stress. In line with our data, it
has been shown that Se, plays a protective role against oxidative stress.
Açıklama
Anahtar Kelimeler
Keywords: fructose, selenium, chorioallantoic membrane, antioxidant
Kaynak
J CLIN EXP INVEST
WoS Q Değeri
Scopus Q Değeri
Cilt
14
Sayı
2
Künye
Sanli Esme O, Savas HB, Sozen ME, Dinc E. The protective role of selenium in an experimental high fructose corn syrup exposure. J CLIN EXP INVEST. 2023;14(2):em00814. https://doi.org/10.29333/jcei/12998.