The Diagnostic Role Of End-Tidal CO2 To Distinguish Unstable Angina Pectoris In Patients With Chest Pain

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dc.authorid0000-0001-6985-6112en_US
dc.authorwosidHCH-3800-2022en_US
dc.contributor.authorGünlü, Serhat
dc.contributor.authorYeşil, Ahmet
dc.contributor.authorKayan, Fethullah
dc.contributor.authorKarahan, Mehmet Zülkif
dc.date.accessioned2023-12-11T12:11:26Z
dc.date.available2023-12-11T12:11:26Z
dc.date.issued2023en_US
dc.departmentMAÜ, Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.description.abstractObjective: Unstable angina pectoris (UAP), one of the acute coronary syndrome (ACS) types, is difficult to identify from non-cardiac chest pain (non-CCP), hence various strategies are applied for accurate diagnosis. This study aims to examine whether non-invasively measured end-tidal CO2 (ETCO2) can detect UAP in patients admitted to the emergency department (ED) with chest pain in the lack of a cardiovascular history. Methods: This research was conducted as a prospective observational study. The individuals were separated into two groups based on the inclusion and exclusion criteria: 75 patients with non-CCP and 75 UAP. Analyses of receiver operating characteristics (ROC) were utilized to define the diagnostic value cutoff. Using univariate regression analysis, the odds ratio of ETCO2 (with 95%CI) was computed for UAP prediction. Results: ETCO2 levels were substantially lower in the UAP group compared to the non-CCP group (p<0.001). Analysis of the ROC curve revealed that a decreased ETCO2 <35 predicted UAP with 78% sensitivity and 89% specificity (AUC:0.81, p <0.001). In addition, the negative predictive value was 71.6%, and the positive predictive value was 79.4%. Patients with UAP were 8.84 times more likely to have ETCO2 <35 than patients with non-CCP. Conclusion: UAP may be differentiated from non-CCP by ETCO2 measured as a non-invasive parameter in patients with chest pain.en_US
dc.identifier.endpage36en_US
dc.identifier.issn2792-0925
dc.identifier.issue2en_US
dc.identifier.startpage29en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12514/4539
dc.identifier.volume3en_US
dc.institutionauthorGünlü, Serhat
dc.language.isoenen_US
dc.relation.ispartofMus Alparslan University Journal of Health Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcute coronary syndrome, non-cardiac chest pain, unstable angina, coronary care unit, end-tidal carbon dioxide.en_US
dc.titleThe Diagnostic Role Of End-Tidal CO2 To Distinguish Unstable Angina Pectoris In Patients With Chest Painen_US
dc.typeArticleen_US

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