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  • Öğe
    Determination of chemical composition and antioxidant, cytotoxic, antimicrobial, and enzyme inhibition activities of Rumex acetosella L. plant extract
    (Springer, 2024) İrtegün Kandemir, Sevgi; Aktepe, Necmettin; Baran, Ayşe; Baran, Mehmet Fırat; Atalar, Mehmet Nuri; Keskin, Cumali; Karadağ, Musa; Eftekhari, Aziz; Alma, Mehmet Hakkı; Zor, Murat; Aliyeva, Immi; Khalilov, Rovshan
    Purpose: The phenolic composition, antioxidant, antimicrobial activity, enzyme inhibition activity, and cytotoxic activity potentials of the plant Rumex acetosella L. (R. acetosella) were examined in this study. Materials and Methods: The chemical composition of R. acetosella methanol extract was identified by the LC–MS/MS method. The antioxidant activity was tested using β-carotene/linoleic acid, DPPH free radical scavenging, ABTS cation radical scavenging, CUPRAC reducing power, and metal chelating activity methods. The cytotoxic activity was determined by the MTT assay using human ovarian adenocarcinoma (Skov-3), glioblastoma (U87), human dermal fibroblasts (HDF), and human colorectal adenocarcinoma (CaCo-2) cell lines. The antimicrobial activity of methanolic extracts was tested on gram-negative (Escherichia coli and Pseudomonas aeuriginosa) and gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis) using the in vitro minimum inhibition concentration method (MIC). Enzyme inhibition activity of R. acetosella methanol extract was measured spectrophotometrically against acetylcholinesterase (AChE) and glutathione S-transferase (GST) enzymes. Results: The findings showed that the major components of the methanol extract content were luteolin-7-O-glucoside (1.599 m/L), polydatin (91,024 m/L), and shikimic acid (0.773 m/L). It was determined that the extract and standard antioxidant (a-tocopherol) results in DPPH•, and ABTS• + tests performed to determine the antioxidant activity were close to each other, and this value was more effective than the standard antioxidant (α-tocopherol) in the CUPRAC test. These results suggested that the plant’s antioxidant potential was higher when compared with reference antioxidant compounds. It was determined that the methanol extract of R. acetosella had a weaker effect on the growth of the tested microorganisms than the antibiotics used as standard. The activity of the GST and AChE enzymes was found to be severely inhibited by the methanol extract of R. acetosella. Conclusion: Based on these findings, R. acetosella L. is a medicinal and commercially beneficial plant that warrants further investigation.
  • Öğe
    The quality problems at low irradiance in the grid-connected photovoltaic systems
    (Springer, 2024) Adak, Süleyman; Cangi, Hasan
    Solar photovoltaic (PV) energy is one of the most prominent topics that have attracted the attention of researchers in recent years. The use of solar energy is increasing rapidly in the world. Although using PV energy has various advantages, it has some disadvantages. Among these disadvantages, power factor (PF) and total harmonic distortion (THD) issues are discussed in this article. When solar PV systems are integrated into the grid, various power quality problems arise. In addition, due to low power quality and high harmonics, power system components overheat and start operating in undesirable regions; causes great damage. The magnitude of PF and THD is dependent on solar irradiation values. In order to determine how the power quality in the grid-connected solar system is affected by changes in solar irradiation (G), results for various irradiation situations are presented and analyzed. In addition, at low irradiance values, the amplitude of harmonic components and reactive power increases, whereas the power factor of the PV system decreases. Low power factor and high amplitude of harmonics cause the efficiency of the solar system to decrease. In this study, PF and THDI values were measured on a particular cloudy day for analysis. An analysis of the solar PV system was conducted using Matlab/simulation program to model the grid-connected PV system. Thus, the analytical expression of the PF and THDI, which are dependent on irradiation, was found with a new method by using the Statistical Package for the Social Sciences (SPSS) program and the curve fitting method. Obtaining the analytical expressions for both solar irradiation (G) and power factor (PF) used the SPSS program and also solar irradiation (G) and total harmonic distortion (THDI) used the MATLAB curve fitting method which contributed to the science comparing to the existing literature. It can be prevented the low power quality by using such these expressions at low solar irradiation cases.
  • Öğe
    Prognostic significance of the chemerin level in coronavirus disease 2019 patients
    (Wolters Kluwer Health, Inc., 2024) Gökdemir, Gül Şahika; Gökdemir, Mehmet Tahir; Araç, Songül; Yokuş, Beran
    Increased serum chemerin levels have been reported in several inflammatory diseases. Few studies have investigated the relationship between chemerin and clinical features of COVID-19. Thus, chemerin may modulate the development and progression of COVID-19. We compared the serum chemerin concentration between patients with and without SARS-CoV-2 infection and its association with the severity and prognosis of COVID-19 pneumonia. This is a prospective, single-center, cross-sectional study. We enrolled COVID-19 patients who presented to our tertiary hospital and healthy controls. The COVID-19 patients were conducted and the dates of symptom onset were recorded. After admission to the hospital and stabilization, blood samples were obtained for routine hemogram, biochemistry, and chemerin. The chemerin level was 37.93 ± 17.3 ng/mL in patients followed in the ICU, 29.41 ± 12.79 ng/mL in inpatients, 30.48 ± 10.86 ng/mL in outpatients, and 25.12 ± 9.82 ng/mL in healthy controls. The difference between patients treated in the ICU and healthy controls was significant (P < .001). The high-sensitivity C-reactive protein (hs-CRP), ferritin, procalcitonin (PCT), and D-dimer levels were significantly higher in the intensive care unit (ICU) group (P < .001). Moreover, the chemerin level of patients who died was significantly higher than that of those who survived (P < .001). The chemerin level was increased in COVID-19 patients and also increased with increasing disease severity. The chemerin level was higher in the COVID-19 patients than healthy controls and was significantly higher in patients who died compared to those who did not.
  • Öğe
    Assessment of preoperative anxiety and negative automatic thoughts in patients waiting for corneal transplantation
    (Publishing Office of the University of Rzeszow, 2024) Tanrıverdi, Seher; Şen, Mehmet Ali; Genç, Hasan
    Introduction and aim. In patients waiting for organ transplantation, increased waiting time can increase anxiety by creating negative automatic thoughts. The aim of this study is to examine the relationship between corneal transplant recipients' negative automatic thoughts and anxiety before organ transplantation. Material and methods. The population of this correlational descriptive study consisted of 108 patients waiting for cornea transplantation in the Eye Bank unit of a hospital in the south east region of Türkiye. The data were obtained from the patients presented to the ophthalmology clinic for transplantation between September and December 2022. A patient information form, the Negative Automatic Thoughts Scale, and the Trait Anxiety Scale were used to collect the data. Percentage distribution, arithmetic mean, logistic regression and correlation analysis were used in the data analysis. Results. It was determined that the mean score of the negative automatic thoughts of the transplant patients participating in the study was 100.69±47.83, and the trait anxiety mean score was 53.06±6.07. There was a positive relationship between negative automatic thoughts and trait anxiety at a moderate level, which was statistically significant (p<0.05, r=0.53). Conclusion. It was determined in the study that the patients' negative automatic thoughts and trait anxiety were high, and their anxiety increased as the negative automatic thoughts increased.
  • Öğe
    An Examination of the Effects of Propolis and Quercetin in a Rat Model of Streptozotocin-Induced Diabetic Peripheral Neuropathy
    (Multidisciplinary Digital Publishing Institute (MDPI), 2024) Türedi, Sibel; Çelik, Hakim; Dağlı, Şeyda Nur; Taşkın, Seyhan; Şeker, Uğur; Deniz, Mustafa
    The purpose of this study was to reveal the combined effects of propolis (P) and quercetin (Q) against diabetic peripheral neuropathy developing with streptozotocin-induced diabetes in rats. Sixty-four adult male rats were divided into eight equal groups: control, P (100 mg/kg/day), Q (100 mg/kg/day), P + Q (100 mg/day for both), diabetes mellitus (DM) (single-dose 60 mg/kg streptozotocin), DM + P, DM + Q, and DM + P + Q. The rats were sacrificed, and blood and sciatic nerve tissues were collected. Blood glucose and malondialdehyde (MDA) levels increased, while IL-6 and total antioxidant status decreased in the DM group (p = 0.016 and p = 0.047, respectively). Ultrastructural findings showed degeneration of the axon and myelin sheath. The apoptotic index (AI %), TNF-α, and IL-1β immunopositivity increased significantly in the DM group (p < 0.001). Morphological structures approaching those of the controls were observed in the DM + P, DM + Q, and DM + P + Q groups. Morphometric measurements increased markedly in all treatment groups (p < 0.001), while blood glucose and MDA levels, AI (%), TNF-α, and IL-1β immunopositivity decreased. In conclusion, the combined effects of propolis and quercetin in diabetic neuropathy may provide optimal morphological protection with neuroprotective effects by reducing hyperglycemia, and these may represent a key alternative supplement in regenerative medicine.
  • Öğe
    Effects of Concomitant Use of N-acetylcysteine and Cyclosporine A on Acetaminophen-induced Acute Kidney Injury in Mice
    (Agricultural Research Communication Centre, 2024) Ozan Kocamüftüoğlu, Gonca; Kaya Tektemür, Nalan; Erdem Güzel, Elif; Tektemur, Ahmet; Ozan, İbrahim Enver
    Background: Acetaminophen (APAP), a commonly used analgesic, causes acute kidney injury (AKI) in overdose although it is rare. Mitochondrial dysfunction plays a major role in the pathophysiology of renal damage, although the exact molecular mechanism is unknown. This study aimed to evaluate the potential therapeutic effect of cyclosporin A (CsA), a mitochondrial membrane permeability transition pore (MPTP) inhibitor, with N-acetylcysteine (NAC) in APAP-induced AKI. Methods: Male BALB/c mice were divided into Control, APAP, APAP+NAC, APAP+CsA and APAP+NAC+CsA groups (n=6). A single dose of APAP (400 mg/kg) was administered intraperitoneally. All other treatments (1200 mg/kg NAC, 50 mg/kg CsA) were performed intraperitoneally 3 h after APAP administration. All animals were decapitated and blood samples and kidney tissue samples were collected for evaluation. Serum creatinine (Cr) and blood urea nitrogen (BUN) levels were measured. The kidney tissue 8-hydroxydeoxyguanosine (8-OHdG), cytochrome c (Cytc) and 3-nitrotyrosine (3-NT) levels and cytochrome c (Cytc) expressions were determined. Result: Increased Cr and BUN levels, histopathological examinations and expressions of 8-OHdG, 3-NT and Cytc were detected in the APAP group. Combined NAC+CsA treatment sufficiently reversed oxidative stress, serum Cr and BUN levels and histopathological alterations induced by APAP. Moreover, cytc levels and renal tubular injury were remarkably reduced by combined drug treatment compared to the APAP+NAC group. These data suggest that the therapeutic effect of combined NAC+CsA treatment in mice with APAP-induced nephrotoxicity can be related to the combination of the antioxidant effect of NAC and the mitochondrial MPTP inhibitor effect of CsA.
  • Öğe
    Tracing royal consumption and socio-symbolism through faunal remains: Zooarchaeology of Iron Age–Urartu Ayanis citadel, Eastern Turkiye
    (Elsevier, 2024) Sıddıq, Abu Bakar; Işıklı, Mehmet
    Despite having a research history of more than one and a half centuries, zooarchaeological investigations within Urartian archaeology are still very limited. This study marks a significant contribution presenting a comprehensive zooarchaeological dataset of 11,977 animal bones and fragments, primarily unearthed from a royal midden at the Urartian site of Ayanis citadel, Eastern Turkiye. The analysis encompasses species identification, age estimation, sex determination, and the identification of taphonomic and pathological changes. Rigorous measurements were taken to establish a robust zooarchaeological dataset. Logarithmic Size Index (LSI) was calculated to identify the morphological characteristics of Ayanis sheep, goats, and cattle, as well as potential sex-based exploitation of these animals. Contextualizing the results with faunal remains from contemporary Urartian sites including Bastam in Iran, and Karmir-Blur, Aramus and Horom in Armenia, this study presents hitherto overlooked archaeological evidence of animal-based consumption behavior and rituals, and possible animal taboos practiced by the Urartian royals and elites. It also offers new opportunities for comparative analyses and discussions for the biometric status of domestic livestock and animal-human interactions within the broader context of the Iron Age in the Lesser Caucasus and West Asia.
  • Öğe
    Robots and emotional intelligence: A thematic analysis
    (Elsevier, 2024) Seyitoğlu, Faruk; Ivanov, Stanislav
    The research on emotional intelligence in social robots is growing. This paper provides a thematic analysis of the studies on robots and emotional intelligence, synthesising and evaluating current knowledge and research topics. In addition, based on the thematic analysis of the studies, it also provides a conceptual framework explaining the emotional intelligence of robots that includes both actors (human and robot) in a human-robot interaction setting. The findings are based on the analysis of 252 studies published until the end of 2022 and indexed in the Scopus database. The results unveiled two main themes (robot design-technical developments and characteristics and human-robot interaction), including sub-themes and topics that emerged in the literature. Finally, the themes and sub-themes were evaluated through a critical discussion to develop a conceptual framework for robots and emotional intelligence.
  • Öğe
    Bodily boundaries transgressed: corporal alteration through ornamentation in the Pre-Pottery Neolithic at Boncuklu Tarla, Türkiye
    (Cambridge University Press, 2024) Kodaş, Ergül; Baysal, Emma L.; Özkan, Kazım
    Lack of contextual evidence for the use of small personal ornaments means that much of our understanding of ornamentation traditions within archaeological cultures is reconstructed from ethnographic comparisons. New in situ finds from the areas around the ears and mouth in burials at Boncuklu Tarla, a Neolithic settlement in Türkiye, add a novel dimension to the interpretation of stone 'tokens' or 'plugs'. This article presents a new typology for these artefacts and argues for their use as ear ornaments or labrets in a practice involving significant and lasting corporal alteration.
  • Öğe
    Equal employment opportunity and diversity in restaurant labor: perspectives of restaurant employees and managers in the USA
    (Emerald Publishing, 2024) Seyitoğlu, Faruk; Atsız, Ozan; Acar, Ayşegül
    Purpose: This study was designed to contribute to the extant literature by discovering the perceptions of restaurant employees and managers toward equal opportunities in restaurant labor and working in a diversity-rich restaurant work environment. Design/methodology/approach: A qualitative research approach was utilized. Through in-depth interviews, data were collected purposefully from restaurant workers in different positions (e.g. managers, servers, chefs and cooks) in the USA. Findings: As a result of content analysis, different perspectives emerged on equal employment opportunity and diversity in restaurant labor. While some employees and managers believe that restaurant labor has equal employment opportunities, others think there is a lack of equal employment opportunity and partial equal employment opportunity in the industry. Most participants perceive working in a diversity-rich restaurant work environment as beneficial (an opportunity to learn about different cultures and an opportunity to learn different experiences and approaches). Originality/value: To the best of our knowledge, this is the first paper to explore employees' and managers' perceptions of equal employment opportunity and diversity in the hospitality labor context, specifically restaurant labor. Therefore, the research findings will create value for scholars to understand the view on equal employment opportunity and diversity in restaurant labor. Further, it will assist practitioners in designing their labor structure regarding equal employment opportunity and diversity management for the future.
  • Öğe
    Nutrition Literacy and Quality of Life of University Students: Evidence from a Cross-Sectional Survey
    (Mashhad University of Medical, 2024) Aslan Ceylan, Jiyan; Bayındır Gümüş, Aylin
    Background and Objectives: Nutrition literacy is a concept that improves individuals' diet quality, and quality of life and contributes to enhancing their general health by using and interpreting nutrition-related information correctly. This study purposed to determine the nutritional literacy and quality of life levels of university students and relate them with anthropometric measurements. Materials and Methods: This is a cross-sectional study and was conducted with 374 university students over the age of 18 at a state university. Nutrition literacy was assessed by using the Evaluation Instrument of Nutrition Literacy on Adults (EINLA), and quality of life was evaluated with the World Health Organization's Quality of Life Questionnaire (Turkish_WHOQOL-BREF). Waist, middle-upper arm, neck circumference, body weight, and height were measured in accordance with appropriate techniques by researchers. Independent t and One-Way ANOVA tests were used to determine differences between two and more than two mean values. Pearson correlation analysis was used to detect relationships between scores of total EINLA, its sections, total Turkish_WHOQOL-BREF and its dimensions, and other variables. Results: The mean EINLA and WHOQOL-BREF scores of the participants were 25.3±4.7 (borderline) and 54.3±15.1, respectively. While the EINLA score varied according to gender, faculty (health sciences vs others), and degree (1 to 4), the WHOQOL-BREF score varied according to gender and living place (home vs dormitory). EINLA and WHOQOL-BREF scores of BMI (underweight to obese), waist circumference, and neck circumference (normal vs at risk) groups were not different. It was found positive significant relationships between the second section of EINLA (reading comprehension and interpretation) and psychological health, the third section of EINLA (food groups), and social relationships (p<0.05). Conclusion: Nutrition literacy, anthropometric measurements, and quality of life of university students are affected by a multifactorial situation.
  • Öğe
    Corn processing by pulsed electric fields with respect to microbial inactivation and improvement of seed vigour
    (Elsevier, 2024) Akdemir Evrendilek, Gülhan; Atmaca, Bahar; Uzuner, Sibel
    Pulsed electric field (PEF) treatment of corn grains to improve seed vigour and inactivation of endogenous microflora by energies ranging from 1.20 to 28.8 J were applied to determine effectiveness of applied energies on germination rate (GR), normal seedling rate (NSR), electrical conductivity (EC), ability to germinate under salt (100- and 200 mM salt) and cold (at 10 °C for 7 days and at 25 °C for 5 days) stresses. Moreover, the effect of PEF treatments was further investigated for the inactivation of total aerobic mesophilic bacteria (TAMB), total mold and yeast (TMY), and inactivation rate (%) of Aspergillus parasiticus. Increased energy provided 11.10 % increase in GR, 21.22 % increase in NSR, 95.50 % increase in germination at 10 °C for 7 days. Germination under stress conditions revealed 32.53 %, 68.35 %, and 76 % increase in germination at 25 °C for 5 days, under 100 mM- and 200 mM NaCI salt stresses. Inactivation on the mean initial TAMB and TMY were approximately 9.25 and 7.93 log, respectively, with 63.33 ± 0.22 % reduction in A. parasiticus culture. PEF treated corn seedlings had stronger and taller body formation with stronger roots. The most optimal processing parameters were detected as 300 Hz, 28.80 J, and 19.78 sec. PEF treatment carries a high potential to improve corn vigour with inactivation of surface microflora.
  • Öğe
    The effect of virtual rainforest and a white noise mobile application on satisfaction, tolerance, comfort, and vital signs during arthroscopy
    (Churchill Livingstone, 2024) Genç, Hasan; Tanriverdi, Seher; Sait Akar, Mehmet
    Background and purpose: This study was conducted to investigate the effect of Virtual Rainforest (VRF) and a White Noise (WN) mobile applications on patient satisfaction, tolerance, comfort, and vital signs during arthroscopic knee surgery. Methods: This is a randomized, controlled, interventional study. The study was completed with a total of 93 participants, 31 in the VRF group, 31 in the WN group, and 31 in the control group. Data were collected using a Patient Information Form and a Visual Analog Scale for satisfaction, tolerance, and comfort. Results: The results of study showed that there were significant increases in tolerance, satisfaction, comfort, respiratory rate, and oxygen saturation levels and significant decreases in heart rate, systolic and diastolic blood pressures in both VRF and WN groups (p < .05). In the control group, no significant difference was found between the means of the variables before and after the procedure (p > .05). Conclusion: According to the results of the study, VRF and WN applied during the arthroscopy procedure increased satisfaction, tolerance, and comfort in patients and had a positive effect on vital signs. Trial and protocol registration:, NCT05992714.
  • Öğe
    Synthesis and characterization of novel magnetic nano-catalyst (Fe3O4@SiO2@EDDHA-Fe) and their hydrogen production activity
    (Elsevier, 2024) Umaz, Adil
    Due to irreparable crises for nature and people, replacing fossil fuel-based energy with green energy sources is a necessity for nature and humanity. Hydrogen is considered a clean energy transport due to its high energy density, environmental friendliness, high efficiency, and recyclable nature. This study generated hydrogen through NaBH4 ethanolysis. In hydrogen production studies, there are very few studies with magnetic nano catalysts and very few studies with cheap transition metals. In order to contribute to the literature in this field, in this study, Fe3O4@SiO2@EDDHA-Fe was produced for the first time and used in hydrogen production studies. Fe3O4@SiO2@EDDHA-Fe synthesis was successfully carried out and hydrogen production was successfully implemented. The study also utilized FT-IR, XRD, VSM, BET, and SEM-EDX methods to characterize the structural, physical, and chemical properties of MNCs. The average particle diameter and magnetization value of Fe3O4@SiO2@EDDHA-Fe were 12.81 nm and 30.6 emu/g, respectively. The catalysis experiment designed with 50 mg Fe3O4@SiO2@EDDHA-Fe and 93.75 mM NaBH4 generated 840 mL H2/g NaBH4 298 K and 947 mL H2/g NaBH4 318 K in 5-min duration, respectively. At room temperature, the hydrogen generation rate (HGR) and activation energy (Ea) of Fe3O4@SiO2@EDDHA-Fe reaction were calculated as 1040 mL H2/gcat·min and 5.39 kJ/mol, respectively. After the sixth cycle, the reusability test of Fe3O4@SiO2@EDDHA-Fe reaction still retained approximately 87% of the initial hydrogen production volume. The study concluded that Fe3O4@SiO2@EDDHA-Fe is a promising catalyst in hydrogen production from NaBH4 ethanolysis, as it is affordable and easy to prepare compared to other expensive catalysts.
  • Öğe
    The effect of the mathematics bag early education program
    (Routledge, 2024) Ergel, Abdülbaki; Aydoğan, Yasemin
    In this study, the effect of the Mathematics Bag Early Education Program (MAÇEP) on the mathematics skills (number/counting, geometry, measurement) of 57–69-month-old preschool children was investigated. A quasi-experimental design with a pretest, posttest, follow-up test, and control group were used in the study. The study group consisted of 22 children attending preschool education and their parents. In the study, MACEP was applied to the experimental group in the form of 50 activities for 12 wk outside the preschool education program. Data were collected using the Early Mathematics Test (EMAT) and Parent Focus Group Interview Form. Mann Whitney U Test, Wilcoxon Signed Rank Test, Friedman Test and content analysis were used to analyze the data. At the end of the study, it was determined that MACEP effectively improved the mathematics skills (number/counting, geometry, measurement) of 57–69-month-old children in the experimental group and the retention continued after the experimental period.
  • Öğe
    Effect of Delivery Method on Breastfeeding Status in Primiparous Mothers Within the First 24 Hours
    (Springer, 2024) Yeşil, Yeşim; Öner, Serap; Dinç Çelik, Gülbiye; Bay, Habibe; Ekşioğlu, Aysun; Ceber Turfan, Esin
    Objective: This study aims to evaluate the effect of the delivery method on breastfeeding status of primiparous mothers during the first 24 hours. Methods: In this descriptive and analytical study, the sample consisted of 126 primiparous mothers with vaginal (n = 54) and cesarean (n = 72) deliveries. The research data were collected in a hospital through a personal information form and LATCH. Breastfeeding was assessed at the 6th, 12th, and 24th hours within the first 24-hour period after the delivery. Results: A total of 83.3% of mothers with vaginal delivery started out breastfeeding in the first hour, while the rate was 43.1% for mothers with cesarean delivery. A total of 94.4% of mothers who had vaginal birth gave their babies colostrum, whereas the rate was 80.6% for mothers who had a cesarean birth. While there were no statistically significant differences in Applications 1 and 3 between the LATCH scores of mothers with vaginal and cesarean deliveries, Application 2 produced a significant difference (p < .05). Conclusions: Delivery method influenced the breastfeeding behavior and had an impact particularly on initiation of breastfeeding in the first hour.
  • Öğe
    Comparison of chemical and antimicrobial properties of different nanoparticles synthesized from Verbascum x calcicolum Hub.-Mor. Hybrid
    (Elsevier, 2024) Ercan, Leyla; Günbegi Çalışkan, Emine; Kılıç, Murat
    Recent advances in nanoparticle synthesis have led to an increase in the use of environmentally acceptable plant-derived nanoparticles, given their wide range of applications. Due to their stability and several advantageous characteristics, selenium nanoparticles also stand out in these investigations in addition to metallic nanoparticles like silver, gold, iron, and zinc. These nanoparticles' favorable qualities for human health, such as antioxidant and antibacterial activities, are being studied in addition to their chemical characteristics. This investigation aimed to produce zinc oxide nanoparticles (VcZnO) and selenium nanoparticles (VcSe) from hybrid Verbascum x calcicolum Hub.-Mor. And to examine their antioxidant and antimicrobial properties. Utilizing the disk diffusion method and well methods, its antibacterial capabilities were studied. In vitro antioxidant capabilities were also assessed utilizing the DPPH, FRAP, and CUPRAC techniques. As a result, it emerged that zinc oxide nanoparticles synthesized from hybrid Verbascum x calcicolum were effective on gram-positive bacteria and gram-negative bacteria such as Staphylococcus aureus (MIC = 160 mg/ml for VcZnO), Pseudomonas aeruginosa (MIC = 80 mg/ml for VcZnO), Klebsiella pneumoniae (MIC = 40 mg/ml for VcZnO and, MIC = 120 mg/ml for VcSe), Escherichia coli (MIC = 20 mg/ml for VcZnO). While selenium nanoparticles are more favorable in terms of antioxidant capabilities, zinc nanoparticles demonstrate stronger antibacterial properties than selenium nanoparticles. Thus, it has been discovered that the use of different nanoparticles of various plants can be more efficient in different applications. It has also been found that Verbascum x calcicolum is a material that can be used successfully in nanoparticle synthesis.
  • Öğe
    Misspecified expectations in an open economy
    (Elsevier, 2024) Yılmaz, Yusuf Ömür; Çiçekçi, Cumhur
    In the past two decades, Turkey has experienced multiple changes in its monetary policy regime. To analyse how these policy changes affect the behaviours of households and firms, some behavioural parameters are incorporated into a small open economy New Keynesian model. Our approach consists of four phases. First, we assess the impacts of the behavioural parameters on the model and find that higher values of the parameters increase the effects of expectations on the model. Second, for the period between 2006 and 2021, the model is estimated for the Turkish economy and the findings show that both households and firms are more forward-looking in their decision making. Moreover, the current variables have a weak effect on the nominal interest rate, and the inertial nominal interest rate has a strong effect on it. Third, we analyse the evolution of the model parameters over the period and find that the behavioural parameters tend to increase, while the monetary policy becomes more inertial. Finally, we conclude that the Central Bank should follow Domestic Inflation-based Taylor rule to minimise welfare loss.
  • Öğe
    The effect of frailty levels of older individuals on their mental well-being and depression levels
    (Wiley, 2024) Bıçak Ayık, Derya; Cengiz, Zeliha; Işık, Kevser
    Background: Frailty has become an important public health issue. This study was conducted to determine the effect of frailty levels of older individuals on their mental well-being and depression levels. Methods: This descriptive cross-sectional study was conducted with a total of 325 older individuals aged 60 years and over. A demographic questionnaire form, the FRAIL Frailty Scale, the Warwick-Edinburgh Mental Well-Being Scale, and the Geriatric Depression Scale-Short Form were used to collect data. Data were evaluated using the SPSS 25.0 package program. Number, percentage, mean, standard deviation, Chi-square, correlation, and multiple regression analyses were used. Results: The mean age of the older individuals was 69.56 ± 7.75 years, and the variables of age, education level, income status, the person they were living with, regular medication use, forgetting to take medication, urinary incontinence, hospitalisation, and accidents were found to affect both frailty and depression (P < 0.05). There was a positive correlation between frailty and depression (r: 0.460, P < 0.001) and a negative correlation between mental frailty and well-being (r: -0.391, P < 0.001). Socio-demographic variables, depression, and mental well-being had a 40% effect on frailty (P < 0.001). Conclusion: Depression status and mental well-being level are related to frailty, so negativity in one of them negatively affects the other. In line with these results, it is recommended to determine the level of depression and mental well-being of older individuals with high risk of frailty, and according to the results of the research, to provide care and support regarding the predictors affecting frailty.
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    Evaluation of nurses' and midwives' knowledge and attitudes towards recognizing violence against women
    (Women's Health and Action Research Center, 2024) Dönmez, Ayşegül; Yeşil, Yeşim
    The study was cross-sectional research that surveyed 410 nurses and midwives from March 2020 to March 2021 in Turkey. The aim of this study was to evaluate the knowledge and attitudes of nurses and midwives towards recognizing violence against women. The "Scale for Nurses' and Midwives' Recognition of the Symptoms of Violence against Women" were used. The average total scale score was 20.3 ± 3.2. The score of participants who are receiving postgraduate education, working in the field of gynaecology and obstetrics, and considering intervention as a professional responsibility when encountering a woman who has experienced violence was found to be significantly higher than the other groups (p<.05). It is important for midwives and nurses to be aware of signs of violence to identify violence against women. Providing education to midwives and nurses regarding signs of violence against women will contribute to the recognition, prevention, and awareness of violence.