Black box in overactive bladder: Central sensitization and its relationship with urinary symptom severity and quality of life

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dc.authorid0000-0003-3110-9976en_US
dc.contributor.authorToprak Şelenay, Ceyda
dc.contributor.authorAltay, Hafize
dc.contributor.authorBülbül, Saliha Beste
dc.contributor.authorOskay, Kemal
dc.date.accessioned2024-01-17T10:55:36Z
dc.date.available2024-01-17T10:55:36Z
dc.date.issued2024en_US
dc.departmentMAÜ, Fakülteler, Sağlık Bilimleri Fakültesi, Fizyoterapi ve Rehabilitasyon Bölümüen_US
dc.description.abstractAim: To examine central sensitization (CS), and to investigate the relationship between CS, and urinary symptom severity, and quality of life (QoL) in women with overactive bladder (OAB). Materials and methods: A total of 144 women with OAB included the study. CS with the Central Sensitization Inventory (CSI), urinary symptom with the Overactive Bladder Questionnaire-Version 8 (OAB-V8), bladder diary and Patients' Perception of Intensity of Urgency Scale (PPIUS) and QoL with the King's Health Questionnaire (KHQ) were assessed. Results: It was found that 47.9% (n = 69) of women with OAB had CS. It was observed that the CSI score was related to the OAB-V8 score (ρ = 0.327; p < 0.001) and the average number of voids/day (ρ = 0.291; p < 0.001). Additionally, urgency severity was higher in women with OAB with CS than in women with OAB without CS (p = 0.006). There was a relationship between the CSI score and KHQ-incontinence impact (ρ = 0.250; p = 0.012), KHQ-personal relationship (ρ = 0.253; p = 0.002), KHQ-sleep/energy (ρ = 0.180; p = 0.031), KHQ-emotional state (ρ = 0.310; p < 0.001) and KHQ-severity measurement scores (ρ = 0.391; p < 0.001). Conclusion: In this study, it was observed that the majority of women with OAB had CS. It was found that more severe symptoms of CS were associated with worse urinary symptom severity and QoL in these patients. It may be beneficial to evaluate CS in the management of OAB and to consider CS when determining treatment strategies.en_US
dc.identifier.citationCelenay, S. T., Altay, H., Bulbul, S. B., & Oskay, K. (2024). Black box in overactive bladder: Central sensitization and its relationship with urinary symptom severity and quality of life. Neurourology and urodynamics, 10.1002/nau.25394. Advance online publication. https://doi.org/10.1002/nau.25394en_US
dc.identifier.doi10.1002/nau.25394en_US
dc.identifier.pmid38221860en_US
dc.identifier.scopus2-s2.0-85182486101en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.1002/nau.25394
dc.identifier.urihttps://hdl.handle.net/20.500.12514/5690
dc.identifier.wosWOS:001143208500001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAltay, Hafize
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofNeurourol Urodynamicsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCentral sensitizationen_US
dc.subjectOveractive bladderen_US
dc.subjectQuality of lifeen_US
dc.subjectWomen's healthen_US
dc.titleBlack box in overactive bladder: Central sensitization and its relationship with urinary symptom severity and quality of lifeen_US
dc.typeArticleen_US

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