Examination of the effects of kefir on healing factors in a mice burn model infected with E.coli, S.aureus and P.aeruginosa using qRT-PCR

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dc.authorid0000-0002-7855-5343en_US
dc.contributor.authorÇetik Yıldız, Songül
dc.contributor.authorDemir, Cemil
dc.contributor.authorAyhancı, Adnan
dc.date.accessioned2022-12-21T05:37:00Z
dc.date.available2022-12-21T05:37:00Z
dc.date.issued2023en_US
dc.departmentMAÜ, Meslek Yüksekokulları, Sağlık Hizmetleri Meslek Yüksekokulu, Tıbbi Hizmetler ve Teknikler Bölümüen_US
dc.description.abstractBurn areas are susceptible to bacterial growth and infections, particularly in cases with lengthy periods of hospital stay. Burn wound healing, which involves various molecular and cellular mechanisms, continues to be a significant problem. Growth factors and cytokines play an active and vital role in wound healing. In the present study, the effects of kefir on wound healing in a 2nd-degree mouse burn model infected with e.coli, s.aureus and p.aeruginosa were investigated in vitro. In order to clarify the effects of kefir in the wound healing process, the macroscopic changes in kefir-applied scar tissue as well as wound depth and width were examined and IL-1α, IL-1β, IL-6, IL-8, IL-10 and TNF-α, VEGF, TGF-β protein levels were determined using the qRT-PCR method. The findings of the present study show that kefir has a positive impact on the factors playing a role in wound healing and accelerates the healing process.en_US
dc.identifier.citationYildiz, S. C., Demir, C., & Ayhanci, A. (2022). Examination of the effects of kefir on healing factors in a mice burn model infected with E. coli, S. aureus and P. aeruginosa using qRT-PCR. Burns.en_US
dc.identifier.doi10.1016/j.burns.2022.08.006en_US
dc.identifier.issue2
dc.identifier.pmid36064692en_US
dc.identifier.scopus2-s2.0-85138504666en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.1016/j.burns.2022.08.006
dc.identifier.urihttps://hdl.handle.net/20.500.12514/3177
dc.identifier.volume49
dc.identifier.wosWOS:000951198100001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÇetik Yıldız, Songül
dc.institutionauthorDemir, Cemil
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofBurnsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBurn wounden_US
dc.subjectCytokine
dc.subjectGrowth factors
dc.subjectMice
dc.subjectWound healing
dc.titleExamination of the effects of kefir on healing factors in a mice burn model infected with E.coli, S.aureus and P.aeruginosa using qRT-PCRen_US
dc.typeArticleen_US

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