Relationship Between Lymph Node Metastasis and Lymph Node Density and Preoperative Neutrophil-Lymphocyte Ratio in Patients Undergoing Radical Cystectomy
Yükleniyor...
Dosyalar
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
UROONKOLOJI BULTENI-BULLETIN OF UROONCOLOGY
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: This study aimed to evaluate the relationship between the preoperative neutrophil-lymphocyte ratio (NLR) and lymph node metastasis and lymph node
density after radical cystectomy in patients with invasive urinary bladder cancer.
Materials and Methods: Data of 89 patients who underwent radical cystectomy were examined. Our study included only cases with stage 2 urothelial bladder
cancer. They were classified according to the lymph node status based on the surgical specimen. Patients with negative results were classified as group 1 and those
with positive results as group 2. Patients in group 2 were further evaluated in two subgroups according to their lymph node density. Accordingly, group 2A consisted
of patients with lymph node density of <20%, and group 2B involved those with lymph node density of ≥20%. Groups were compared statistically according to NLR.
Results: Of the patients, 71 (79.8%) were male. The patients’ mean ages and neutrophil and lymphocyte counts were 67.36±8.64 years, 6.89±3.02 K/µL, and
3.08±2.18 K/µL, respectively. NLRs of groups 1 and 2 were 2.80±2.25 and 4.59±2.97, respectively. The relationship between group 1 and 2 tumors was significant
(p=0.008). NLR values were 3.82±2.49 and 5.20±3.25 in groups 2A and 2B, respectively. However, no significant relationship was found between these values
(p=0.235).
Conclusion: Although no positive correlation was found between NLR and lymph node density, we think that this inflammation marker is an invaluable parameter
to predict lymph node metastasis
Açıklama
Anahtar Kelimeler
Lymphocyte, neutrophil, bladder cancer, cystectomy
Kaynak
UROONKOLOJI BULTENI-BULLETIN OF UROONCOLOGY
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
Sayı
Künye
Kölükçü, E., Atılgan, D., Kuyucu, Y. E., Özbek, L. M., & Unsal, V. (2021). Relationship Between Lymph Node Metastasis and Lymph Node Density and Preoperative Neutrophil-Lymphocyte Ratio in Patients Undergoing Radical Cystectomy. In The Bulletin of Urooncology (Vol. 20, Issue 3, pp. 168–173). Galenos Yayinevi. https://doi.org/10.4274/uob.galenos.2021.1809
