The association of allergic rhinitis severity with neutrophil-lymphocyte and platelet-lymphocyte ratio in children

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dc.authorid0000-0002-0187-3810en_US
dc.authorid0000-0001-7164-3933en_US
dc.contributor.authorCansever, Murat
dc.contributor.authorSarı, Neslihan
dc.date.accessioned2023-06-09T07:12:25Z
dc.date.available2023-06-09T07:12:25Z
dc.date.issued2022en_US
dc.departmentMAÜ, Fakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kulak Burun ve Boğaz Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractObjective: The aim of the study was to investigate the relationship between the severity of allergic rhinitis (AR) and neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) in pediatric patients. Methods: This study is a retrospective, cross-sectional, and observational study including 200 AR patients and 160 healthy controls. Of the patients, 39% were boys with a mean age of 10.5 years. The study included children with persistent and intermittent AR. Of the controls, 50.6% were boys with a mean age of 10.3 years. We compared NLR and PLR from blood test between study and control groups. They were also compared according to AR severity within the patient group. Results: The NLR was 1.64±1.29 in the study group whereas 1.18±0.31 in the control group. The PLR was 102.72±31.20 in the study group whereas 79.36±11.72 in the control group. When NLR and PLR were compared between groups, we found statistically significant differences in both NLR and PLR (p=0.003, p=0.001, respectively). We found a statistically significant difference when comparing both NLR and PLR in patients with intermittent and persistent AR. These rates increased with disease severity (p=0.000, p=0.000, respectively). Conclusion: Both NLR and PLR are useful markers for the diagnosis and severity of AR. Clinicians can use these markers to assess disease severity in pediatric patients at the beginning of the diagnostic process.en_US
dc.identifier.citationCansever, M., & Sari, N. (2022). The association of allergic rhinitis severity with neutrophil-lymphocyte and platelet-lymphocyte ratio in children. Northern Clinics of İstanbul, 9(6), 602-609.en_US
dc.identifier.doi10.14744/nci.2022.96236en_US
dc.identifier.endpage609en_US
dc.identifier.issue6en_US
dc.identifier.pmid36685620en_US
dc.identifier.scopus2-s2.0-85164724594en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage602en_US
dc.identifier.trdizinid1167590en_US
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/36685620/
dc.identifier.urihttps://hdl.handle.net/20.500.12514/3513
dc.identifier.volume9en_US
dc.identifier.wosWOS:000945686500009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherNorthern Clinics of İstanbulen_US
dc.relation.ispartofNorthern Clinics of İstanbulen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAeroallergens; neutrophil-lymphocyte ratio; pediatric allergic rhinitis; platelet-lymphocyte ratioen_US
dc.titleThe association of allergic rhinitis severity with neutrophil-lymphocyte and platelet-lymphocyte ratio in childrenen_US
dc.typeArticleen_US

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