Evaluation of Hematological Parameters After Transcatheter Aortic Valve Replacement

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dc.contributor.authorKarahan, Mehmet Zülkif
dc.contributor.authorAktan, Adem
dc.contributor.authorGüzel, Tuncay
dc.contributor.authorKılıç, Raif
dc.contributor.authorGünlü, Serhat
dc.contributor.authorDemir, Muhammed
dc.contributor.authorErtaş, Faruk
dc.date.accessioned2023-08-01T07:00:10Z
dc.date.available2023-08-01T07:00:10Z
dc.date.issued2023en_US
dc.departmentMAÜ, Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.description.abstractAlthough transcatheter aortic valve replacement (TAVR) is safe and effective, mortality and bleeding events post procedure are important. The present study investigated the changes in hematologic parameters to evaluate whether they predict mortality or major bleeding. We enrolled 248 consecutive patients (44.8% male; mean age 79.0 ± 6.4 years) undergoing TAVR. In addition to demographic and clinical examination, blood parameters were recorded before TAVR, at discharge, 1 month and 1 year. Hemoglobin levels before TAVR 12.1 ± 1.8 g/dL, 10.8 ± 1.7 g/dL at discharge, 11.7 ± 1.7 g/dL at first month, 11.8 ± 1.4 g/dL at first year (Hemoglobin values compared with pre-TAVR, P < .001, P = .019, P = .047, respectively). Mean platelet volume (MPV) before TAVR 8.72 ± 1.71 fL, 8.16 ± 1.46 fL at discharge, 8.09 ± 1.44 fL at first month, 7.94 ± 1.18 fL at first year (MPV values compared with pre-TAVR, P < .001, P < .001, P < .001, respectively). Other hematologic parameters were also evaluated. Hemoglobin, platelet count, MPV, and red cell distribution width before the procedure, at discharge, and at the first year did not predict mortality and major bleeding in receiver operating characteristic analysis. After multivariate Cox regression analysis, hematologic parameters were not independent predictors of in-hospital mortality, major bleeding, and death at 1 year after TAVR.en_US
dc.identifier.citationKarahan, M. Z., Aktan, A., Güzel, T., Kılıç, R., Günlü, S., Demir, M., & Ertaş, F. (2023). Evaluation of Hematological Parameters After Transcatheter Aortic Valve Replacement. Angiology, 00033197231177397.en_US
dc.identifier.doi10.1177/000331972311773en_US
dc.identifier.pmid37236655en_US
dc.identifier.scopus2-s2.0-85163027281en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.1177/000331972311773
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/37236655/
dc.identifier.urihttps://hdl.handle.net/20.500.12514/3570
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85163027281&origin=SingleRecordEmailAlert&dgcid=raven_sc_affil_en_us_email&txGid=44e2207cdbf520568e7252084972b8a5
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:001002856000001
dc.identifier.wosWOS:001002856000001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Journalsen_US
dc.relation.ispartofAngiology .en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectaortic stenosis; hematologic parameters; hemoglobin; mean platelet volume; red cell distribution width; transcatheter aortic valve implantation.en_US
dc.titleEvaluation of Hematological Parameters After Transcatheter Aortic Valve Replacementen_US
dc.typeArticleen_US

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