Comparison of Evolut-R 34 mm Valve and Smaller Evolut-R Valves in Patients Undergoing Transcatheter Aortic Valve Implantation and Determination of Mild Paravalvular Leak Predictors

dc.authorid0000-0003-0505-9784en_US
dc.contributor.authorKılıç, Raif
dc.contributor.authorGüzel, Tuncay
dc.contributor.authorAktan, Adem
dc.contributor.authorDemir, Muhammed
dc.contributor.authorGünlü, Serhat
dc.contributor.authorArslan, Bayram
dc.contributor.authorErtaş, Faruk
dc.date.accessioned2024-02-20T10:27:35Z
dc.date.available2024-02-20T10:27:35Z
dc.date.issued2024en_US
dc.departmentMAÜ, Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.description.abstractObjective: The main purpose of this study was to evaluate and compare the in-hospital, 1-month and 1-year post-procedure outcomes of patients treated with Evolut-R 34 mm and Evolut-R 23/26/29 mm devices. Additionally, the study aimed to identify factors that could predict the occurrence of ≥ mild paravalvular leaks (PVL). Methods: Between April 2015 and May 2022, 269 consecutive patients who underwent transcatheter aortic valve implantation (TAVI) with Evolut-R 34 mm (n = 66, 24.5%) and Evolut-R 23/26/29 mm (n = 203, 75.5%) devices in a single center were retrospectively analyzed. Results: Patients in the Evolut-R 34 mm group had a lower female sex ratio (16.7% vs. 66.5%, P < .001, respectively), ejection fraction (50.7 ± 10.1% vs. 54.5 ± 9.3%, P= .016, respectively), and mean aortic gradient (7.4 ± 3.3 vs. 9.2 ± 5.0, P= .026, respectively) compared to the Evolut-R 23/26/29 mm group. The groups did not exhibit any statistically significant distinctions with regard to technical success, the need for a permanent pacemaker, occurrences of stroke, major vascular complications, PVL, major adverse cardiovascular and cerebrovascular events, or mortality. Peak velocity was confirmed as a significant predictor of ≥mild PVL in both patient groups in the receiver operating characteristic curve analysis. In logistic regression analysis; In patients with Evolut-R 34 mm valve, pre-TAVI aortic valve peak velocity (odds ratio (OR) = 23.202; P= .019) and calcium volume 800 Hounsfield Units (mm3) (OR = 1.017; P < .001) were independent predictors of ≥mild PVL. Conclusion: The Evolut-R 34 mm valve has shown comparable in-hospital results with smaller valve sizes. Pre-TAVI aortic valve peak velocity and calcium volume predicted ≥ mild PVL in Evolut-R 34 mm patients.en_US
dc.identifier.citationKılıç, R. (2024). Comparison of evolut-r 34 mm valve and smaller evolut-r valves in patients undergoing transcatheter aortic valve implantation and determination of mild paravalvular leak predictors. The Anatolian Journal of Cardiology, 109-117. https://doi.org/10.14744/anatoljcardiol.2023.3563en_US
dc.identifier.doi10.14744/anatoljcardiol.2023.3563en_US
dc.identifier.endpage117en_US
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85184757221en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage109en_US
dc.identifier.urihttps://doi.org/10.14744/anatoljcardiol.2023.3563
dc.identifier.urihttps://hdl.handle.net/20.500.12514/5783
dc.identifier.volume28en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorAktan, Adem
dc.institutionauthorGünlü, Serhat
dc.language.isoenen_US
dc.publisherTurkish Society of Cardiologyen_US
dc.relation.ispartofAnatolian Journal of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEvolut-R 34 mm peak velocityen_US
dc.subjectParavalvular leaken_US
dc.subjectTranscatheter aortic valve implantationen_US
dc.titleComparison of Evolut-R 34 mm Valve and Smaller Evolut-R Valves in Patients Undergoing Transcatheter Aortic Valve Implantation and Determination of Mild Paravalvular Leak Predictorsen_US
dc.typeArticleen_US

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