Comparison of Evolut-R 34 mm Valve and Smaller Evolut-R Valves in Patients Undergoing Transcatheter Aortic Valve Implantation and Determination of Mild Paravalvular Leak Predictors
dc.authorid | 0000-0003-0505-9784 | en_US |
dc.contributor.author | Kılıç, Raif | |
dc.contributor.author | Güzel, Tuncay | |
dc.contributor.author | Aktan, Adem | |
dc.contributor.author | Demir, Muhammed | |
dc.contributor.author | Günlü, Serhat | |
dc.contributor.author | Arslan, Bayram | |
dc.contributor.author | Ertaş, Faruk | |
dc.date.accessioned | 2024-02-20T10:27:35Z | |
dc.date.available | 2024-02-20T10:27:35Z | |
dc.date.issued | 2024 | en_US |
dc.department | MAÜ, Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı | en_US |
dc.description.abstract | Objective: The main purpose of this study was to evaluate and compare the in-hospital, 1-month and 1-year post-procedure outcomes of patients treated with Evolut-R 34 mm and Evolut-R 23/26/29 mm devices. Additionally, the study aimed to identify factors that could predict the occurrence of ≥ mild paravalvular leaks (PVL). Methods: Between April 2015 and May 2022, 269 consecutive patients who underwent transcatheter aortic valve implantation (TAVI) with Evolut-R 34 mm (n = 66, 24.5%) and Evolut-R 23/26/29 mm (n = 203, 75.5%) devices in a single center were retrospectively analyzed. Results: Patients in the Evolut-R 34 mm group had a lower female sex ratio (16.7% vs. 66.5%, P < .001, respectively), ejection fraction (50.7 ± 10.1% vs. 54.5 ± 9.3%, P= .016, respectively), and mean aortic gradient (7.4 ± 3.3 vs. 9.2 ± 5.0, P= .026, respectively) compared to the Evolut-R 23/26/29 mm group. The groups did not exhibit any statistically significant distinctions with regard to technical success, the need for a permanent pacemaker, occurrences of stroke, major vascular complications, PVL, major adverse cardiovascular and cerebrovascular events, or mortality. Peak velocity was confirmed as a significant predictor of ≥mild PVL in both patient groups in the receiver operating characteristic curve analysis. In logistic regression analysis; In patients with Evolut-R 34 mm valve, pre-TAVI aortic valve peak velocity (odds ratio (OR) = 23.202; P= .019) and calcium volume 800 Hounsfield Units (mm3) (OR = 1.017; P < .001) were independent predictors of ≥mild PVL. Conclusion: The Evolut-R 34 mm valve has shown comparable in-hospital results with smaller valve sizes. Pre-TAVI aortic valve peak velocity and calcium volume predicted ≥ mild PVL in Evolut-R 34 mm patients. | en_US |
dc.identifier.citation | Kılıç, R. (2024). Comparison of evolut-r 34 mm valve and smaller evolut-r valves in patients undergoing transcatheter aortic valve implantation and determination of mild paravalvular leak predictors. The Anatolian Journal of Cardiology, 109-117. https://doi.org/10.14744/anatoljcardiol.2023.3563 | en_US |
dc.identifier.doi | 10.14744/anatoljcardiol.2023.3563 | en_US |
dc.identifier.endpage | 117 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.scopus | 2-s2.0-85184757221 | en_US |
dc.identifier.scopusquality | N/A | en_US |
dc.identifier.startpage | 109 | en_US |
dc.identifier.uri | https://doi.org/10.14744/anatoljcardiol.2023.3563 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12514/5783 | |
dc.identifier.volume | 28 | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.institutionauthor | Aktan, Adem | |
dc.institutionauthor | Günlü, Serhat | |
dc.language.iso | en | en_US |
dc.publisher | Turkish Society of Cardiology | en_US |
dc.relation.ispartof | Anatolian Journal of Cardiology | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Evolut-R 34 mm peak velocity | en_US |
dc.subject | Paravalvular leak | en_US |
dc.subject | Transcatheter aortic valve implantation | en_US |
dc.title | Comparison of Evolut-R 34 mm Valve and Smaller Evolut-R Valves in Patients Undergoing Transcatheter Aortic Valve Implantation and Determination of Mild Paravalvular Leak Predictors | en_US |
dc.type | Article | en_US |