Green synthesis and evaluation of antipathogenic, antioxidant, and anticholinesterase activities of gold nanoparticles (Au NPs) from Allium cepa L. peel aqueous extract
Yükleniyor...
Dosyalar
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SpringerLink
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Gold nanoparticles (Au NPs) have potentially therapeutic properties as they are synthesized via biomolecules as reducing
and stabilizing agent(s). The aim of this study is to develop an easy and eco-friendly method for the synthesis of Au NPs
using extracts from the Allium cepa (AC) red peel (skin) extract and investigate the antibacterial and antioxidant activity and
also inhibitory efects on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes. UV–Vis peak at~564 nm
confrmed the Au NPs absorbance. TEM images revealed the formation of Au NPs with mostly spherical shapes and sizes
between 6.08 and 54.20 nm. FTIR analysis confrmed the important biological compounds responsible for the reduction of
gold. The strong absorption property of Au NPs was studied by EDX. The produced Au NPs demonstrated signifcant antibacterial and antifungal activity against the bacterial and fungal strains tested, as well as efcient inhibitory activity against
both AChE and BChE enzymes. The highest antimicrobial activities were found against Staphylococcus aureus (0.06° mg/
ml) and Candida albicans (0.06° mg/ml). The antioxidant test fndings revealed that AC-Au NPs had lesser activity when
compared to normal antioxidants. The Au NPs showed excellent inhibitory efcacy against AChE and BChE. The proposed
green technique could encourage the innocuous generation of Au NPs, implying therapeutic possibilities.
Açıklama
Anahtar Kelimeler
Allium cepa · Antioxidant · Anticholinesterase activity · Gold nanoparticles · Plant-based nanoparticles
Kaynak
Biomass Conversion and Biorefinery
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
Sayı
Künye
İpek, P., Baran, M. F., Baran, A., Hatipoğlu, A., Keskin, C., Yildiztekin, M., ... & Cho, W. C. (2023). Green synthesis and evaluation of antipathogenic, antioxidant, and anticholinesterase activities of gold nanoparticles (Au NPs) from Allium cepa L. peel aqueous extract. Biomass Conversion and Biorefinery, 1-10.
