Synthesis and Characterization of Bionanomaterials and Evaluation of Their Antioxidant, Antibacterial, and DNA Cleavage Activities
Yükleniyor...
Dosyalar
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Chemistry Select
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, the hexagonal boron nitride (hBN) (1), poly-levodopa (P-L(DP) (2), P-L(DP) coated hBN (hBN@P(L-DP)) (3), and silver nanoparticles (AgNPs) decorated hBN@P(L-DP) (hBN@P(L-DP)-AgNPs) (4) were synthesized and characterized by multiple spectroscopic techniques. Additionally, their biological properties such as antioxidant, antibacterial, and DNA cleavage activities were determined. It is worth noting that, products 3 and 4 were newly synthesized structures. The antioxidant activities of all the nanomaterials 1, 2, 3, and 4 nanomaterials were investigated using some tests such as DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging and reducing power ability. Among the synthesized nanomaterials, product 2 exhibited the highest radical scavenging (64.8±1.94 %) and reducing power activity (0.61±0.017) at a concentration of 200 mg L−1. Product 4 was determined to have antibacterial activity against all three Gram-positive and three Gram-negative test bacteria. In addition, all the nanomaterials were tested for cleavage activity using pBR 322 plasmid DNA, as a result of which it was determined that only product 4 showed the ability of cleavage from both chains of DNA.
Açıklama
Anahtar Kelimeler
Antioxidant activity, DNA cleavage activity, L-dopa, Nanomaterials, Silver Nanoparticles
Kaynak
Chemistry Select
WoS Q Değeri
Q3
Scopus Q Değeri
N/A
Cilt
6
Sayı
17
Künye
Tarhan, T., Dündar, A., Okumuş, V., & Çulha, M. (2021). Synthesis and Characterization of Bionanomaterials and Evaluation of Their Antioxidant, Antibacterial, and DNA Cleavage Activities. In ChemistrySelect (Vol. 6, Issue 17, pp. 4217–4223). Wiley. https://doi.org/10.1002/slct.202004773
Bağlantı
https://www.scopus.com/record/display.uri?eid=2-s2.0-85107541586&doi=10.1002%2fslct.202004773&origin=inward&txGid=7f95105611a8af9bf3cd4dfb47e5e856&featureToggles=FEATURE_NEW_METRICS_SECTION:1
https://hdl.handle.net/20.500.12514/2669
https://www.webofscience.com/wos/woscc/full-record/WOS:000656879800023?AlertId=d383397b-4355-449e-9419-70f9e0e77c15&SID=F62lurvzvUoMJrDI6Mq
https://doi.org/10.1002/slct.202004773
https://hdl.handle.net/20.500.12514/2669
https://www.webofscience.com/wos/woscc/full-record/WOS:000656879800023?AlertId=d383397b-4355-449e-9419-70f9e0e77c15&SID=F62lurvzvUoMJrDI6Mq
https://doi.org/10.1002/slct.202004773
