Synthesis and Characterization of Bionanomaterials and Evaluation of Their Antioxidant, Antibacterial, and DNA Cleavage Activities

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dc.contributor.authorTarhan, Tuba
dc.contributor.authorDündar, Abdurrahman
dc.contributor.authorOkumuş, Veysi
dc.contributor.authorÇulha, Mustafa
dc.date.accessioned2021-07-14T08:35:57Z
dc.date.available2021-07-14T08:35:57Z
dc.date.issued2021en_US
dc.departmentMAÜ, Meslek Yüksekokulları, Sağlık Hizmetleri Meslek Yüksekokulu, Tıbbi Hizmetler ve Teknikler Bölümüen_US
dc.description.abstractIn this study, the hexagonal boron nitride (hBN) (1), poly-levodopa (P-L(DP) (2), P-L(DP) coated hBN (hBN@P(L-DP)) (3), and silver nanoparticles (AgNPs) decorated hBN@P(L-DP) (hBN@P(L-DP)-AgNPs) (4) were synthesized and characterized by multiple spectroscopic techniques. Additionally, their biological properties such as antioxidant, antibacterial, and DNA cleavage activities were determined. It is worth noting that, products 3 and 4 were newly synthesized structures. The antioxidant activities of all the nanomaterials 1, 2, 3, and 4 nanomaterials were investigated using some tests such as DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging and reducing power ability. Among the synthesized nanomaterials, product 2 exhibited the highest radical scavenging (64.8±1.94 %) and reducing power activity (0.61±0.017) at a concentration of 200 mg L−1. Product 4 was determined to have antibacterial activity against all three Gram-positive and three Gram-negative test bacteria. In addition, all the nanomaterials were tested for cleavage activity using pBR 322 plasmid DNA, as a result of which it was determined that only product 4 showed the ability of cleavage from both chains of DNA.en_US
dc.identifier.citationTarhan, T., Dündar, A., Okumuş, V., & Çulha, M. (2021). Synthesis and Characterization of Bionanomaterials and Evaluation of Their Antioxidant, Antibacterial, and DNA Cleavage Activities. In ChemistrySelect (Vol. 6, Issue 17, pp. 4217–4223). Wiley. https://doi.org/10.1002/slct.202004773
dc.identifier.doi10.1002/slct.202004773en_US
dc.identifier.endpage4223en_US
dc.identifier.issue17en_US
dc.identifier.scopus2-s2.0-85107541586en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage4217en_US
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85107541586&doi=10.1002%2fslct.202004773&origin=inward&txGid=7f95105611a8af9bf3cd4dfb47e5e856&featureToggles=FEATURE_NEW_METRICS_SECTION:1
dc.identifier.urihttps://hdl.handle.net/20.500.12514/2669
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000656879800023?AlertId=d383397b-4355-449e-9419-70f9e0e77c15&SID=F62lurvzvUoMJrDI6Mq
dc.identifier.urihttps://doi.org/10.1002/slct.202004773
dc.identifier.volume6en_US
dc.identifier.wosWOS:000656879800023en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherChemistry Selecten_US
dc.relation.ispartofChemistry Selecten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidant activity, DNA cleavage activity, L-dopa, Nanomaterials, Silver Nanoparticlesen_US
dc.titleSynthesis and Characterization of Bionanomaterials and Evaluation of Their Antioxidant, Antibacterial, and DNA Cleavage Activitiesen_US
dc.typeArticleen_US

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